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1
Progress and prediction of multicomponent quantification in complex systems with practical LC-UV methods
Xi Chen, Zhao Yang, Yang Xu, Zhe Liu, Yanfang Liu, Yuntao Dai, Shilin Chen
2023, 13(2): 142-155. doi: 10.1016/j.jpha.2022.11.011
Abstract(2220) PDF(226)
2
Potential of RP-UHPLC-DAD-MS for the qualitative and quantitative analysis of sofosbuvir in film coated tablets and profiling degradants
María del Mar Contreras, Aránzazu Morales-Soto, Antonio Segura-Carretero, Javier Valverde
2017, 7(4): 208-213.
Abstract(82) PDF(136)
3
Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory application
Dan Li, Zhou Fang, Qiang Shi, Nicholas Zhang, Binsheng Gong, Weida Tong, Ahmet F. Coskun, Joshua Xu
2023, 13(7): 691-693. doi: 10.1016/j.jpha.2023.06.013
Abstract(590) PDF(84)
4
Single-cell analyses reveal cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon cancer
Xiaofan Sun, Lisha Zhou, Yi Wang, Guoliang Deng, Xinran Cao, Bowen Ke, Xiaoqi Wu, Yanhong Gu, Haibo Cheng, Qiang Xu, Qianming Du, Hongqi Chen, Yang Sun
2023, 13(7): 726-744. doi: 10.1016/j.jpha.2023.04.013
Abstract(473) PDF(83)
5
Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and nanotechnology
Yi Lu, Qiulan Luo, Xiaobin Jia, James P. Tam, Huan Yang, Yuping Shen, Xin Li
2023, 13(3): 239-254. doi: 10.1016/j.jpha.2022.12.001
Abstract(746) PDF(77)
6
Ginsenoside Rk3 is a novel PI3K/AKT-targeting therapeutics agent that regulates autophagy and apoptosis in hepatocellular carcinoma
Linlin Qu, Yannan Liu, Jianjun Deng, Xiaoxuan Ma, Daidi Fan
2023, 13(5): 463-482. doi: 10.1016/j.jpha.2023.03.006
Abstract(542) PDF(75)
7
Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors
Yan Chen, Xingguo Hou, Dapeng Li, Jin Ding, Jiayue Liu, Zilei Wang, Fei Teng, Hongjun Li, Fan Zhang, Yi Gu, Steven Yu, Xueming Qian, Zhi Yang, Hua Zhu
2023, 13(4): 367-375. doi: 10.1016/j.jpha.2023.02.011
Abstract(592) PDF(74)
8
Single-cell analysis of cellular heterogeneity and interactions in the ischemia-reperfusion injured mouse intestine
Lianhong Yin, Meng Gao, Lina Xu, Yan Qi, Lan Han, Jinyong Peng
2023, 13(7): 760-775. doi: 10.1016/j.jpha.2023.02.002
Abstract(453) PDF(73)
9
Rabdosia serra alleviates dextran sulfate sodium salt-induced colitis in mice through anti-inflammation, regulating Th17/Treg balance, maintaining intestinal barrier integrity, and modulating gut microbiota
Hongyi Li, Yi Wang, Shumin Shao, Hui Yu, Deqin Wang, Chuyuan Li, Qin Yuan, Wen Liu, Jiliang Cao, Xiaojuan Wang, Haibiao Guo, Xu Wu, Shengpeng Wang
2022, 12(6): 824-838. doi: 10.1016/j.jpha.2022.08.001
Abstract(525) PDF(70)
10
Celastrol targeting Nedd4 reduces Nrf2-mediated oxidative stress in astrocytes after ischemic stroke
Zexuan Hong, Jun Cao, Dandan Liu, Maozhu Liu, Mengyuan Chen, Fanning Zeng, Zaisheng Qin, Jigang Wang, Tao Tao
2023, 13(2): 156-169. doi: 10.1016/j.jpha.2022.12.002
Abstract(442) PDF(67)
11
Temporal dynamics of microglia-astrocyte interaction in neuroprotective glial scar formation after intracerebral hemorrhage
Jingwei Zheng, Haijian Wu, Xiaoyu Wang, Guoqiang Zhang, Jia'nan Lu, Weilin Xu, Shenbin Xu, Yuanjian Fang, Anke Zhang, Anwen Shao, Sheng Chen, Zhen Zhao, Jianmin Zhang, Jun Yu
2023, 13(8): 862-879. doi: 10.1016/j.jpha.2023.02.007
Abstract(431) PDF(65)
12
Microneedle-based interstitial fluid extraction for drug analysis: Advances, challenges, and prospects
Shuwen Ma, Jiaqi Li, Lixia Pei, Nianping Feng, Yongtai Zhang
2023, 13(2): 111-126. doi: 10.1016/j.jpha.2022.12.004
Abstract(520) PDF(60)
13
Single-cell transcriptome analysis uncovers underlying mechanisms of acute liver injury induced by tripterygium glycosides tablet in mice
Qiuyan Guo, Jiangpeng Wu, Qixin Wang, Yuwen Huang, Lin Chen, Jie Gong, Maobo Du, Guangqing Cheng, Tianming Lu, Minghong Zhao, Yuan Zhao, Chong Qiu, Fei Xia, Junzhe Zhang, Jiayun Chen, Feng Qiu, Jigang Wang
2023, 13(8): 908-925. doi: 10.1016/j.jpha.2023.03.004
Abstract(410) PDF(59)
14
Targeted metabolomics reveals the aberrant energy status in diabetic peripheral neuropathy and the neuroprotective mechanism of traditional Chinese medicine JinMaiTong
Bingjia Zhao, Qian Zhang, Yiqian He, Weifang Cao, Wei Song, Xiaochun Liang
2024, 14(2): 225-243. doi: 10.1016/j.jpha.2023.09.007
Abstract(430) PDF(57)
15
High-throughput transcriptional profiling of perturbations by Panax ginseng saponins and Panax notoginseng saponins using TCM-seq
Junyun Cheng, Jie Chen, Jie Liao, Tianhao Wang, Xin Shao, Jinbo Long, Penghui Yang, Anyao Li, Zheng Wang, Xiaoyan Lu, Xiaohui Fan
2023, 13(4): 376-387. doi: 10.1016/j.jpha.2023.02.009
Abstract(462) PDF(57)
16
Discovery of human pancreatic lipase inhibitors from root of Rhodiola crenulata via integrating bioactivity-guided fractionation, chemical profiling and biochemical assay
Li-Juan Ma, Xu-Dong Hou, Xiao-Ya Qin, Rong-Jing He, Hao-Nan Yu, Qing Hu, Xiao-Qing Guan, Shou-Ning Jia, Jie Hou, Tao Lei, Guang-Bo Ge
2022, 12(4): 683-691. doi: 10.1016/j.jpha.2022.04.002
Abstract(475) PDF(56)
17
Optimization of nucleic acid extraction methods for rapid detection in pandemic situations or diseases with high prevalence
Hesti Lina Wiraswati, Ilma Fauziah Ma'ruf, Savira Ekawardhani, Lia Faridah, Amila Laelalugina, Harry Septanto, Imam Damar Djati, Shabarni Gaffar, Asif Awaludin
2023, 13(12): 1577-1579. doi: 10.1016/j.jpha.2023.08.005
Abstract(278) PDF(55)
18
Neutrophil elastase: From mechanisms to therapeutic potential
Weilin Zeng, Yingqiu Song, Runze Wang, Rong He, Tianlu Wang
2023, 13(4): 355-366. doi: 10.1016/j.jpha.2022.12.003
Abstract(616) PDF(53)
19
Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission
Xiao-Ling Liang, Lan Ouyang, Nan-Nan Yu, Zheng-Hua Sun, Zi-Kang Gui, Yu-Long Niu, Qing-Yu He, Jing Zhang, Yang Wang
2023, 13(10): 1168-1182. doi: 10.1016/j.jpha.2023.06.005
Abstract(389) PDF(52)
20
SUMO1 regulates post-infarct cardiac repair based on cellular heterogeneity
Zhihao Liu, Xiaozhi Liu, Li Liu, Ying Wang, Jie Zheng, Lan Li, Sheng Li, Han Zhang, Jingyu Ni, Chuanrui Ma, Xiumei Gao, Xiyun Bian, Guanwei Fan
2023, 13(2): 170-186. doi: 10.1016/j.jpha.2022.11.010
Abstract(381) PDF(52)
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