Development status of novel spectral imaging techniques and application to traditional Chinese medicine

Qi Wang; Yong Zhang; Baofeng Yang

doi:10.1016/j.jpha.2023.07.007

Volume 13 Issue 11

Nov. 2023

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Article Navigation > Journal of Pharmaceutical Analysis > 2023 > 13(11): 1269-1280

Qi Wang, Yong Zhang, Baofeng Yang. Development status of novel spectral imaging techniques and application to traditional Chinese medicine[J]. Journal of Pharmaceutical Analysis, 2023, 13(11): 1269-1280. doi: 10.1016/j.jpha.2023.07.007

Citation:

Qi Wang, Yong Zhang, Baofeng Yang. Development status of novel spectral imaging techniques and application to traditional Chinese medicine[J]. Journal of Pharmaceutical Analysis, 2023, 13(11): 1269-1280. doi: 10.1016/j.jpha.2023.07.007

Citation:

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Development status of novel spectral imaging techniques and application to traditional Chinese medicine

doi: 10.1016/j.jpha.2023.07.007

Qi Wang^a,
Yong Zhang^{b,c,d
,
,},
Baofeng Yang^{b,c,e
,
,}

a. Department of Medicinal Chemistry and Natural Medicinal Chemistry, College of Pharmacy, Harbin Medical University, Harbin, 150081, China;
b. Department of Pharmacology (The State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China;
c. Research Unit of Noninfectious Chronic Diseases in Frigid Zone, Chinese Academy of Medical Sciences, Harbin, 150081, China;
d. Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Harbin, 150086, China;
e. Department of Pharmacology and Therapeutics, Melbourne School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences University of Melbourne, Melbourne, VIC, 3010, Australia

Funds:

This work was supported by the National Key R&D Program of China (Grant No.: 2017YFC1702003) and the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (Grant No.: 2019–12M-5-078).

Received Date: Apr. 05, 2023
Accepted Date: Jul. 12, 2023
Rev Recd Date: Jul. 10, 2023
Publish Date: Jul. 29, 2023

Abstract

Abstract

Traditional Chinese medicine (TCM) is a treasure of the Chinese nation, providing effective solutions to current medical requisites. Various spectral techniques are undergoing continuous development and provide new and reliable means for evaluating the efficacy and quality of TCM. Because spectral techniques are noninvasive, convenient, and sensitive, they have been widely applied to in vitro and in vivo TCM evaluation systems. In this paper, previous achievements and current progress in the research on spectral technologies (including fluorescence spectroscopy, photoacoustic imaging, infrared thermal imaging, laser-induced breakdown spectroscopy, hyperspectral imaging, and surface enhanced Raman spectroscopy) are discussed. The advantages and disadvantages of each technology are also presented. Moreover, the future applications of spectral imaging to identify the origins, components, and pesticide residues of TCM in vitro are elucidated. Subsequently, the evaluation of the efficacy of TCM in vivo is presented. Identifying future applications of spectral imaging is anticipated to promote medical research as well as scientific and technological explorations.
- Chinese medicine,
- Spectral imaging,
- Fluorescence spectroscopy,
- Photoacoustic imaging

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