Combining transformer and 3DCNN models to achieve co-design of structures and sequences of antibodies in a diffusional manner

doi: 10.1016/j.jpha.2025.101267

• Yue Hu^a,d , 
• Feng Tao^b,c , 
• Jiajie Xu^a , 
• WenJun Lan^a , 
• Jing Zhang^a , 
• Wei Lan^e

• a School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250300, Shandong, China;

• b The second affiliated hospital of zhejiang university, School of Medicine, Zhejiang University, Hangzhou, 310053, China;

• c Binjiang Institute of Zhejiang University, Hangzhou, 310053, China;

• d Kyiv College, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250300, Shandong, China;

• e College of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830011, China