Ginsenoside Rb₁ inhibits cardiomyocyte apoptosis and rescues ischemic myocardium by targeting Caspase-3

doi: 10.1016/j.jpha.2024.101142

• Chenhui Zhong^a , 
• Liyuan Ke^a , 
• Fen Hu^b , 
• Zuan Lin^a , 
• Shuming Ye^a , 
• Ziyao Zheng^a , 
• Shengnan Han^a , 
• Zan Lin^a , 
• Yuying Zhan^a , 
• Yan Hu^c , 
• Peiying Shi^{d ,  ,}  , 
• Lei Wen^{e ,  ,}  , 
• Hong Yao^{a,f ,  ,} 

• a Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou 350122, China;

• b Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350002, China;

• c Public Technology Service Center, Fujian Medical University, Fuzhou 350122, China;

• d Department of Traditional Chinese Medicine Resource and Development, College of Bee Science and Biomedicine, Fujian Agriculture and Forestry University, Fuzhou 350002, China;

• e The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China;

• f Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, Fujian Medical University, Fuzhou, China