Perspective on <i>in vivo</i> SPME for human applications: Starting from monitoring doxorubicin during lung chemo-perfusion

Wei Zhou; Runshan Will Jiang; Barbara Bojko; Janusz Pawliszyn

doi:10.1016/j.jpha.2023.12.008

Volume 14 Issue 7

Jul. 2024

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Wei Zhou, Runshan Will Jiang, Barbara Bojko, Janusz Pawliszyn. Perspective on in vivo SPME for human applications: Starting from monitoring doxorubicin during lung chemo-perfusion[J]. Journal of Pharmaceutical Analysis, 2024, 14(7): 100918. doi: 10.1016/j.jpha.2023.12.008

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Wei Zhou, Runshan Will Jiang, Barbara Bojko, Janusz Pawliszyn. Perspective on in vivo SPME for human applications: Starting from monitoring doxorubicin during lung chemo-perfusion[J]. Journal of Pharmaceutical Analysis, 2024, 14(7): 100918. doi: 10.1016/j.jpha.2023.12.008

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Perspective on in vivo SPME for human applications: Starting from monitoring doxorubicin during lung chemo-perfusion

doi: 10.1016/j.jpha.2023.12.008

a. Department of Chemistry, University of Waterloo, Waterloo, ON N2L 3G1, Canada;
b. Department of Pharmacodynamics and Molecular Pharmacology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 85-089, Bydgoszcz, Poland;
c. Department of Chemistry, University of Waterloo, Waterloo, ON N2L 3G1, Canada

Funds:

We would like to thank Natural Science and Engineering Research Council (NSERC) of Canada and National Institute of Mental Health (Grant No.: R01MH129641) for their financial support.

Publish Date: Dec. 12, 2023

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References(5)

References

[1]	A. Roszkowska, K. Łuczykowski, N. Warmuzińska, et al., SPME and Related Techniques in Biomedical Research, Evolution of solid phase microextraction technology, Royal Society of Chemistry (2018) 357-418.
[2]	A. Napylov, N. Reyes-Garces, G. Gomez-Rios, et al., In vivo solid-phase microextraction for sampling of oxylipins in brain of awake, moving rats, Angew. Chem. Int. Ed Engl. 59 (2020) 2392-2398.
[3]	B. Bojko, N. Looby, M. O lkowicz, et. al., Solid phase microextraction chemical biopsy tool for monitoring of doxorubicin residue during in vivo lung chemo-perfusion, J. Pharm. Anal. 11 (2021) 37-47.
[4]	W. Zhou, E. Nazdrajić, J. Pawliszyn, High-Throughput and Rapid Screening of Drugs of Abuse in Saliva by Multi-Segment Injection Using Solid-Phase Microextraction-Automated Microfluidic Open Interface-Mass Spectrometry, Anal. Chem. 95 (2023) 6367-6376.
[5]	J. Bogusiewicz, K. Burlikowska, K. Łuczykowski, New chemical biopsy tool for spatially resolved profiling of human brain tissue in vivo, Sci. Rep. 11 (2021) 19522.