N. Satheeshkumar, S. Shantikumar, R. Srinivas. Pioglitazone:A review of analytical methods[J]. Journal of Pharmaceutical Analysis, 2014, (5): 295-302. doi: 10.1016/j.jpha.2014.02.002
Citation:
N. Satheeshkumar, S. Shantikumar, R. Srinivas. Pioglitazone:A review of analytical methods[J]. Journal of Pharmaceutical Analysis, 2014, (5): 295-302. doi: 10.1016/j.jpha.2014.02.002
N. Satheeshkumar, S. Shantikumar, R. Srinivas. Pioglitazone:A review of analytical methods[J]. Journal of Pharmaceutical Analysis, 2014, (5): 295-302. doi: 10.1016/j.jpha.2014.02.002
Citation:
N. Satheeshkumar, S. Shantikumar, R. Srinivas. Pioglitazone:A review of analytical methods[J]. Journal of Pharmaceutical Analysis, 2014, (5): 295-302. doi: 10.1016/j.jpha.2014.02.002
Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Hyderabad NIPER-H, Balanagar, Hyderabad 500037, India
National Center for Mass Spectrometry, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500607, India
Pioglitazone is an oral anti-hyperglycemic agent. It is used for the treatment of diabetes mellitus type 2. It selectively stimulates nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma). It was the tenth-best-selling drug in the U.S. in 2008. This article examines published analytical methods reported so far in the literature for the determination of pioglitazone in biological samples and pharmaceutical formulations. They include various techniques like electrochemical methods, spectrophotometry, capillary electrophoresis, high-performance liquid chromatography, liquid chromatography-electrospray ionization-tandem mass spectrometry and high-performance thin layer chromatography.
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