Butyrate-based ionic liquid for improved oral bioavailability and synergistic anti-colorectal cancer activity of glycyrol

doi: 10.1016/j.jpha.2025.101359

• Ziyu Wang^a , 
• Xingyue Shi^b , 
• Yikang Shu^a , 
• Ran Gao^a , 
• Ting Sun^a , 
• Mingyue Wu^a , 
• Mingxin Dong^c , 
• Weiguo Wu^a , 
• Ruili Ma^a , 
• Daoquan Tang^a , 
• Min Ye^d , 
• Shuai Ji^{a ,  ,} 

• a Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou 221004, China;

• b Department of Medical Oncology, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou 221004, China;

• c School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510640, China;

• d State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China