Active peptides pursuit from complicated matrices via tracing ligand-protein complex with MS/MS: Chaperone screening for lysozyme as a pilot study

Zihan Zhu; Jiahui Wen; Ting Li; Han Li; Wei Li; Ke Zhang; Pengfei Tu; Wenjing Liu; Yuelin Song

doi:10.1016/j.jpha.2026.101586

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Zihan Zhu, Jiahui Wen, Ting Li, Han Li, Wei Li, Ke Zhang, Pengfei Tu, Wenjing Liu, Yuelin Song. Active peptides pursuit from complicated matrices via tracing ligand-protein complex with MS/MS: Chaperone screening for lysozyme as a pilot study[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2026.101586

Citation:

Zihan Zhu, Jiahui Wen, Ting Li, Han Li, Wei Li, Ke Zhang, Pengfei Tu, Wenjing Liu, Yuelin Song. Active peptides pursuit from complicated matrices via tracing ligand-protein complex with MS/MS: Chaperone screening for lysozyme as a pilot study[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2026.101586

Citation:

Zihan Zhu, Jiahui Wen, Ting Li, Han Li, Wei Li, Ke Zhang, Pengfei Tu, Wenjing Liu, Yuelin Song. Active peptides pursuit from complicated matrices via tracing ligand-protein complex with MS/MS: Chaperone screening for lysozyme as a pilot study[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2026.101586

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Active peptides pursuit from complicated matrices via tracing ligand-protein complex with MS/MS: Chaperone screening for lysozyme as a pilot study

doi: 10.1016/j.jpha.2026.101586

Zihan Zhu^a,b,
Jiahui Wen^a,b,
Ting Li^a,b,
Han Li^a,b,
Wei Li^a,b,
Ke Zhang^a,
Pengfei Tu^a,
Wenjing Liu^{c
,
,},
Yuelin Song^{a
,
,}

a. Modern Research Center for Traditional Chinese Medicine, Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 102401, China;
b. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102401, China;
c. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China

Funds:

This study was financially supported by the National Natural Science Foundation of China (Grant No.: 82474202).

Received Date: Sep. 24, 2025
Accepted Date: Feb. 11, 2026
Rev Recd Date: Feb. 11, 2026
Available Online: Feb. 13, 2026

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References(5)

References

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