Volume 9 Issue 1
Feb.  2019
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Yu Zhang, Rui Zhang, Xiaolin Yang, Honglan Qi, Chengxiao Zhang. Recent advances in electrogenerated chemiluminescence biosensing methods for pharmaceuticals[J]. Journal of Pharmaceutical Analysis, 2019, 9(1): 9-19.
Citation: Yu Zhang, Rui Zhang, Xiaolin Yang, Honglan Qi, Chengxiao Zhang. Recent advances in electrogenerated chemiluminescence biosensing methods for pharmaceuticals[J]. Journal of Pharmaceutical Analysis, 2019, 9(1): 9-19.

Recent advances in electrogenerated chemiluminescence biosensing methods for pharmaceuticals

  • Publish Date: Feb. 10, 2019
  • Electrogenerated chemiluminescence (electrochemiluminescence, ECL) generates species at electrode surfaces, which undergoes electron-transfer reactions and forms excited states to emit light. It has be-come a very powerful analytical technique and has been widely used in such as clinical testing, bio-warfare agent detection, and pharmaceutical analysis. This review focuses on the current trends of molecular recognition-based biosensing methods for pharmaceutical analysis since 2010. It introduces a background of ECL and presents the recent ECL developments in ECL immunoassay (ECLIA), im-munosensors, enzyme-based biosensors, aptamer-based biosensors, and molecularly imprinted poly-mers (MIP)-based sensors. At last, the future perspective for these analytical methods is briefly discussed.
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