Large-scale evaluation of HIV-1 DNA drug resistance testing as a robust tool for clinical decision-making: A nationwide study in China

doi: 10.1016/j.jpha.2025.101513

• Caihong Wu^a , 
• Limin Zhang^a , 
• Zhong Chen^a,b , 
• Wencui Ma^a , 
• Yanhua Fu^c , 
• Ke Yang^b , 
• Mei Liu^d , 
• Yanjun Li^e , 
• Xiaohong Chen^f , 
• Mingjie Hou^g , 
• Min Liu^h , 
• Aihua Dengⁱ , 
• Qingxia Zhao^g , 
• Lukun Zhang^j , 
• Quan Wang^k , 
• Jun Peng^a,l , 
• Yongli Li^m , 
• Keji Deng^a,l , 
• Jingsong Baiⁿ , 
• Hai Long^d , 
• Yaokai Chen^h , 
• Hui Wang^j , 
• Yun He^j , 
• Jin Li^o , 
• Jiahui Guo^a , 
• Bianchuan Cao^p , 
• Yizhi Cui^a , 
• Min Wang^b , 
• Tuofu Zhu^a,l , 
• Jun Yao^q , 
• Tong Wang^{a ,  ,} 

• a State Key Laboratory of Bioactive Molecules and Druggability Assessment, Center of Clinical Laboratory, The First Affiliated Hospital, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China;

• b Department of Infectious Diseases, Institute of HIV/AIDS, The First Hospital of Changsha, Changsha, 410005, China;

• c Department of Infectious Disease, Guiyang Public Health Treatment Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, 550001, China;

• d Department of Antiviral Therapy, The First People's Hospital of Yuexi County, Liangshan, Sichuan, 615000, China;

• e Department of Infectious Diseases, Guangxi AIDS Clinical Treatment Center, The Fourth People's Hospital of Nanning, Nanning, 530023, China;

• f Department of Infectious Diseases, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, China;

• g Department of Infectious Diseases, Henan Infectious Disease Hospital, Zhengzhou, 450015, China;

• h Department of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, 400036, China;

• i Jiangxi Chest Hospital, Nanchang, 330000, China;

• j The Third People's Hospital of Shenzhen, Shenzhen, 518112, China;

• k Department of Laboratory Medicine, Xinjiang Uygur Autonomous Region Infectious Disease Hospital, Urumqi, 830000, China;

• l Guangzhou SupBio Bio-Technologies and Science Co., Ltd., Guangzhou, 510530, China;

• m Dongguan Institute of Microscale and Precision Medical Measurement Co., Ltd., Dongguan, 523808, China;

• n Department of Infectious Diseases, The Third People's Hospital of Kunming, Kunming, 650500, China;

• o Department of Infectious Disease, The Ninth People's Hospital of Dongguan, Dongguan, Guangdong, 523076, China;

• p Department of Infectious Disease, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China;

• q National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China