Carbon dots derived from <i>Poria cocos</i> polysaccharide as an effective “on-off” fluorescence sensor for chromium (VI) detection

Qianqian Huang; Qianqian Bao; Chengyuan Wu; Mengru Hu; Yunna Chen; Lei Wang; Weidong Chen

doi:10.1016/j.jpha.2021.04.004

Volume 12 Issue 1

Feb. 2022

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Article Navigation > Journal of Pharmaceutical Analysis > 2022 > 12(1): 104-112

Qianqian Huang, Qianqian Bao, Chengyuan Wu, Mengru Hu, Yunna Chen, Lei Wang, Weidong Chen. Carbon dots derived from Poria cocos polysaccharide as an effective “on-off” fluorescence sensor for chromium (VI) detection[J]. Journal of Pharmaceutical Analysis, 2022, 12(1): 104-112. doi: 10.1016/j.jpha.2021.04.004

Citation:

Qianqian Huang, Qianqian Bao, Chengyuan Wu, Mengru Hu, Yunna Chen, Lei Wang, Weidong Chen. Carbon dots derived from Poria cocos polysaccharide as an effective “on-off” fluorescence sensor for chromium (VI) detection[J]. Journal of Pharmaceutical Analysis, 2022, 12(1): 104-112. doi: 10.1016/j.jpha.2021.04.004

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Carbon dots derived from Poria cocos polysaccharide as an effective “on-off” fluorescence sensor for chromium (VI) detection

doi: 10.1016/j.jpha.2021.04.004

Anhui Province Key Laboratory of Chinese Medicinal Formula, Anhui University of Chinese Medicine, Hefei, 230012, China

Funds:

This work is financially supported by the Natural Science Foundation of Anhui University of Chinese Medicine (Grant No.: 2018zrzd04), Anhui Provincial Natural Science Foundation (Grant No.: 1908085QH351), Major Science and Technology Projects of Anhui Province (Grant No.: 18030801131), National Key Research and Development Project (Grant No.: 2017YFC1701600), and Anhui Province's Central Special Fund for Local Science and Technology Development (Grant No.: 201907d07050002).

Received Date: Sep. 14, 2020
Accepted Date: Apr. 16, 2021
Rev Recd Date: Apr. 02, 2021
Publish Date: May 01, 2021

Abstract

Abstract

Chromium is a harmful contaminant showing mutagenicity and carcinogenicity. Therefore, detection of chromium requires the development of low-cost and high-sensitivity sensors. Herein, blue-fluorescent carbon quantum dots were synthesized by one-step hydrothermal method from alkali-soluble Poria cocos polysaccharide, which is green source, cheap and easy to obtain, and has no pharmacological activity due to low water solubility. These carbon quantum dots exhibit good fluorescence stability, water solubility, anti-interference and low cytotoxicity, and can be specifically combined with the detection of Cr(VI) to form a non-fluorescent complex that causes fluorescence quenching, so they can be used as a label-free nanosensor. High-sensitivity detection of Cr(VI) was achieved through internal filtering and static quenching effects. The fluorescence quenching degree of carbon dots fluorescent probe showed a good linear relationship with Cr(VI) concentration in the range of 1–100 μM. The linear equation was F₀/F = 0.9942 + 0.01472 [Cr(VI)] (R² = 0.9922), and the detection limit can be as low as 0.25 μM (S/N = 3), which has been successfully applied to Cr(VI) detection in actual water samples herein.
- Carbon dots,
- Alkali-soluble Poria cocos polysaccharide,
- Cr(VI) detection,
- Internal filtering effect,
- Static quenching effect

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References(50)

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