Rajeev Jain, Sanjay Sharma. Glassy carbon electrode modified with multi-walled carbon nanotubes sensor for the quantification of antihistamine drug pheniramine in solubilized systems[J]. Journal of Pharmaceutical Analysis, 2012, 02(1): 56-61. doi: 10.1016/j.jpha.2011.09.013
Citation:
Rajeev Jain, Sanjay Sharma. Glassy carbon electrode modified with multi-walled carbon nanotubes sensor for the quantification of antihistamine drug pheniramine in solubilized systems[J]. Journal of Pharmaceutical Analysis, 2012, 02(1): 56-61. doi: 10.1016/j.jpha.2011.09.013
Rajeev Jain, Sanjay Sharma. Glassy carbon electrode modified with multi-walled carbon nanotubes sensor for the quantification of antihistamine drug pheniramine in solubilized systems[J]. Journal of Pharmaceutical Analysis, 2012, 02(1): 56-61. doi: 10.1016/j.jpha.2011.09.013
Citation:
Rajeev Jain, Sanjay Sharma. Glassy carbon electrode modified with multi-walled carbon nanotubes sensor for the quantification of antihistamine drug pheniramine in solubilized systems[J]. Journal of Pharmaceutical Analysis, 2012, 02(1): 56-61. doi: 10.1016/j.jpha.2011.09.013
Glassy carbon electrode modified with multi-walled carbon nanotubes sensor for the quantification of antihistamine drug pheniramine in solubilized systems
A sensitive electroanalytical method for quantification of pheniramine in pharmaceutical formulation has been investigated on the basis of the enhanced electrochemical response at glassy carbon electrode modified with multi-walled carbon nanotubes in the presence of sodium lauryl sulfate.The experimental results suggest that the phcniramine in anionic surfactant solution exhibits electrocatalytic effect resulting in a marked enhancement of the peak current response.Peak current response is linearly dependent on the concentration of pheniramine in the range 200-1500 μg/mL with correlation coefficient 0.9987.The limit of detection is 58.31 μg/m L.The modified electrode shows good sensitivity and repeatability.
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