SMPD1-mediated sphingolipid metabolism dysregulation in predicting and preventing in-stent restenosis of coronary heart disease patients

doi: 10.1016/j.jpha.2026.101553

• Weiyu Meng^a , 
• Yuyang Sha^a , 
• Ci-ren Zhong-ga^b , 
• Hongxin Pan^a , 
• Xiaobing Zhai^a , 
• Pu Zhen^b , 
• Henry H. Y. Tong^a , 
• Edmundo Patricio Lopes Lao^c , 
• Hongjia Zhang^d , 
• Wenzhi Yang^e,f , 
• Song Cui^{d ,  ,}  , 
• Xiantao Song^{d ,  ,}  , 
• Kefeng Li^{a ,  ,} 

• a Center for Artificial Intelligence Driven Drug Discovery, Faculty of Applied Sciences, Macao Polytechnic University, Macau SAR, 999078, China;

• b Department of Cardiology, Lhasa People's Hospital, Lhasa, Xizang Autonomous Region, 850000, China;

• c Department of Cardiology, Macao Health Bureau, Macau SAR, 999078, China;

• d Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China;

• e State Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China;

• f Haihe Laboratory of Modern Chinese Medicine, Tianjin, 301617, China