Volume 10 Issue 1
Feb.  2020
Turn off MathJax
Article Contents
Shuang Li, Peipei Yu, Ceng Zhou, Ling Tong, Dongxiang Li, Zhiguo Yu, Yunli Zhao. Analysis of pesticide residues in commercially available chenpi using a modified QuEChERS method and GC-MS/MS determination[J]. Journal of Pharmaceutical Analysis, 2020, 10(1): 60-69.
Citation: Shuang Li, Peipei Yu, Ceng Zhou, Ling Tong, Dongxiang Li, Zhiguo Yu, Yunli Zhao. Analysis of pesticide residues in commercially available chenpi using a modified QuEChERS method and GC-MS/MS determination[J]. Journal of Pharmaceutical Analysis, 2020, 10(1): 60-69.

Analysis of pesticide residues in commercially available chenpi using a modified QuEChERS method and GC-MS/MS determination

  • Publish Date: Feb. 15, 2020
  • To ensure the safety of the commercially available chenpi, a convenient and fast analytical method was developed for the determination of 133 pesticide residues in chenpi using gas chromatography-tandem mass spectrometry (GC-MS/MS). In this study, different extraction solvents, redissolution solvents and adsorbents were tested according to the recovery and purification effect to obtain a modified QuEChERS method. The samples were extracted with acetonitrile. During the clean-up step, octadecyl-modified silica (C18) and graphitized carbon black (GCB) were selected, and aminopropyl (NH2) was used instead of primary secondary amine (PSA) because of its weaker ion exchange capacity which had little effect on the recovery of ditalimfos. Samples were quantified by matrix-matched calibration with internal stan-dards. All pesticides showed good linearity in the respective range, both with values of r2 >0.99. The average recoveries of the pesticides spiked samples ranged from 70.0% to 112.2% with the RSDs of 0.2%–14.4%. The modified QuEChERS method was validated and applied to twenty real samples. Five pesticides were found in eight batches, but no pesticide exceeded the maximum residue limits (MRL, MRL reference to European commission).
  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (154) PDF downloads(1) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return