Satar Tursynbolat, Yrysgul Bakytkarim, Jianzhi Huang, Lishi Wang. Ultrasensitive electrochemical determination of metronidazole based on polydopamine/carboxylic multi-walled carbon nanotubes nanocomposites modified GCE[J]. Journal of Pharmaceutical Analysis, 2018, 8(2): 124-130.
Citation: Satar Tursynbolat, Yrysgul Bakytkarim, Jianzhi Huang, Lishi Wang. Ultrasensitive electrochemical determination of metronidazole based on polydopamine/carboxylic multi-walled carbon nanotubes nanocomposites modified GCE[J]. Journal of Pharmaceutical Analysis, 2018, 8(2): 124-130.

Ultrasensitive electrochemical determination of metronidazole based on polydopamine/carboxylic multi-walled carbon nanotubes nanocomposites modified GCE

  • Publish Date: Apr. 10, 2018
  • An ultrasensitive electrochemical sensor based on polydopamine/carboxylic multi-walled carbon nano-tubes (MWCNTs-COOH) nanocomposites modified glassy carbon electrode (GCE) was presented in this work, which has been developed for highly selective and highly sensitive determination of an anti-microbial drug, metronidazole. The preparation of polydopamine/MWCNTs―COOH nanocomposites/GCE sensor is simple and possesses high reproducible, where polydopamine can be coated on the surface of MWCNTs―COOH via a simple electropolymerization process. Under optimized conditions, the proposed sensor showed ultrasensitive determination for metronidazole with a wide linear detection range from 5 to 5000μmol/dm3 and a low detection limit of 0.25μmol/dm3 (S/N = 3). Moreover, the proposed sensor has been successfully applied for the quantitative determination of metronidazole in real drug samples. This work may provide a novel and effective analytical platform for determination of me-tronidazole in application of real pharmaceutical and biological samples analysis.
  • Relative Articles

  • Created with Highcharts 5.0.7Amount of accessChart context menuAbstract Views, HTML Views, PDF Downloads StatisticsAbstract ViewsHTML ViewsPDF Downloads2024-062024-072024-082024-092024-102024-112024-122025-012025-022025-032025-042025-050246810
    Created with Highcharts 5.0.7Chart context menuAccess Class DistributionFULLTEXT: 30.9 %FULLTEXT: 30.9 %META: 65.7 %META: 65.7 %PDF: 3.3 %PDF: 3.3 %FULLTEXTMETAPDF
    Created with Highcharts 5.0.7Chart context menuAccess Area Distribution其他: 2.8 %其他: 2.8 %China: 73.5 %China: 73.5 %France: 2.2 %France: 2.2 %United States: 19.3 %United States: 19.3 %Viet Nam: 2.2 %Viet Nam: 2.2 %其他ChinaFranceUnited StatesViet Nam

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (118) PDF downloads(6) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return