Peng Dong, Na Xu, Bo Fu, Lei Wang. Rapid europium-sensitized fluorescent determination of ulifloxacin, the active metabolite of prulifloxacin, in human serum and urine[J]. Journal of Pharmaceutical Analysis, 2011, 01(1): 46-50.
Citation:
Peng Dong, Na Xu, Bo Fu, Lei Wang. Rapid europium-sensitized fluorescent determination of ulifloxacin, the active metabolite of prulifloxacin, in human serum and urine[J]. Journal of Pharmaceutical Analysis, 2011, 01(1): 46-50.
Peng Dong, Na Xu, Bo Fu, Lei Wang. Rapid europium-sensitized fluorescent determination of ulifloxacin, the active metabolite of prulifloxacin, in human serum and urine[J]. Journal of Pharmaceutical Analysis, 2011, 01(1): 46-50.
Citation:
Peng Dong, Na Xu, Bo Fu, Lei Wang. Rapid europium-sensitized fluorescent determination of ulifloxacin, the active metabolite of prulifloxacin, in human serum and urine[J]. Journal of Pharmaceutical Analysis, 2011, 01(1): 46-50.
A new fluorescent method was developed based on the ulifloxacin-europium (Ⅲ)-sodium dodecylbenzene sulfonate system for the determination of ulifloxacin,the active metabolite of prulifloxacin.Sodium dodecylbenzene sulfonate formed a ternary complex with ulifloxacin-europium (Ⅲ) and significantly enhanced the characteristic fluorescence of europium (Ⅲ).The enhanced fluorescence intensity showed a good linear relationship with the concentration of ulifloxacin in the range of 5.0× 10 8 -2.0× 10-6M with a detection limit of 2.0× 10-10 M (3σ).This method is rapid and sensitive,and has been successfully applied to the determination of ulifloxacin in human urine and serum samples.
Peng Dong, Na Xu, Bo Fu, Lei Wang. Rapid europium-sensitized fluorescent determination of ulifloxacin, the active metabolite of prulifloxacin, in human serum and urine[J]. Journal of Pharmaceutical Analysis, 2011, 01(1): 46-50.
Peng Dong, Na Xu, Bo Fu, Lei Wang. Rapid europium-sensitized fluorescent determination of ulifloxacin, the active metabolite of prulifloxacin, in human serum and urine[J]. Journal of Pharmaceutical Analysis, 2011, 01(1): 46-50.