Volume 1 Issue 1
Feb.  2011
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Peng Dong, Na Xu, Bo Fu, Lei Wang. Rapid europium-sensitized fluorescent determination of ulifloxacin, the active metabolite of prulifloxacin, in human serum and urine[J]. Journal of Pharmaceutical Analysis, 2011, 01(1): 46-50.
Citation: Peng Dong, Na Xu, Bo Fu, Lei Wang. Rapid europium-sensitized fluorescent determination of ulifloxacin, the active metabolite of prulifloxacin, in human serum and urine[J]. Journal of Pharmaceutical Analysis, 2011, 01(1): 46-50.

Rapid europium-sensitized fluorescent determination of ulifloxacin, the active metabolite of prulifloxacin, in human serum and urine

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国家自然科学基金

  • Publish Date: Feb. 10, 2011
  • A new fluorescent method was developed based on the ulifloxacin-europium (Ⅲ)-sodium dodecylbenzene sulfonate system for the determination of ulifloxacin,the active metabolite of prulifloxacin.Sodium dodecylbenzene sulfonate formed a ternary complex with ulifloxacin-europium (Ⅲ) and significantly enhanced the characteristic fluorescence of europium (Ⅲ).The enhanced fluorescence intensity showed a good linear relationship with the concentration of ulifloxacin in the range of 5.0× 10 8 -2.0× 10-6M with a detection limit of 2.0× 10-10 M (3σ).This method is rapid and sensitive,and has been successfully applied to the determination of ulifloxacin in human urine and serum samples.
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      沈阳化工大学材料科学与工程学院 沈阳 110142

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