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Shan Lian, Wenyong Yang, Yan Zeng, Ranran Tang, Kui Wang. Targeted nano-drug delivery systems for tumor immunotherapy[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2025.101408
Citation: Shan Lian, Wenyong Yang, Yan Zeng, Ranran Tang, Kui Wang. Targeted nano-drug delivery systems for tumor immunotherapy[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2025.101408

Targeted nano-drug delivery systems for tumor immunotherapy

doi: 10.1016/j.jpha.2025.101408
  • Received Date: Mar. 10, 2025
  • Accepted Date: Jul. 19, 2025
  • Rev Recd Date: Jun. 24, 2025
  • Available Online: Jul. 29, 2025
  • While being a safe and effective precision therapy strategy, tumor immunotherapy still fails in many patients due to immunosuppressive microenvironment. Emerging evidence has indicated that the targeted nano-drug delivery systems can accurately deliver therapeutic agents to potentiate the efficacy of immunotherapy. This review will outline recent advances in applying targeted nano-drug delivery systems in immunotherapy, with an emphasis on their crucial roles in regulating innate immunity response, adaptive immunity response, and immunogenic cell death. We will also discuss the current challenges and future opportunities for the clinical translation of targeted nano-drug delivery systems for tumor immunotherapy.
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      沈阳化工大学材料科学与工程学院 沈阳 110142

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