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Wei Yang, Jinnian Ge, Mohan Jiang, Nan Zhang, Qinghe Yang, Kaisheng Nan, Qinfu Zhao, Long Wan, Xiaofan Wang. Recent trends in mesoporous carbon-based nanoplatforms for biomedical application[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2025.101383
Citation: Wei Yang, Jinnian Ge, Mohan Jiang, Nan Zhang, Qinghe Yang, Kaisheng Nan, Qinfu Zhao, Long Wan, Xiaofan Wang. Recent trends in mesoporous carbon-based nanoplatforms for biomedical application[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2025.101383

Recent trends in mesoporous carbon-based nanoplatforms for biomedical application

doi: 10.1016/j.jpha.2025.101383
Funds:

Grants from "Xing Liao Talent Program" of Liaoning Province (No. XLYC2203156) and Doctoral Start-up Foundation of Liaoning Province (No. 20170520001) are greatly acknowledged.

  • Received Date: Jan. 19, 2025
  • Accepted Date: Jun. 26, 2025
  • Rev Recd Date: May 26, 2025
  • Available Online: Jul. 04, 2025
  • Mesoporous carbon nanoparticles (MCNs) have received considerable attention for biomedical applications due to their unique structural features, including high specific surface area, adjustable pore size, and remarkable biocompatibility. These properties have addressed key challenges such as inefficiencies in drug loading and release, minimizing the side effects associated with conventional treatments. In this review, the classification and the research progress of MCNs are summarized firstly, the preparation and modification techniques to enhance their functionality and properties are further reviewed, the main physicochemical properties are introduced as well, highlighting their contributions to MCNs in applications. In addition, the biomedical applications of MCNs are emphasized, including tumor therapy, tumor theranostics, antibacterial, delivery of active molecules and biological detection. Finally, the prospects and challenges of clinical application based on MCNs are analyzed to provide an effective reference and lay the foundation for further research.
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