Gege Zhu, Li Ge, Xinyu Li, Bing Niu, Qin Chen, Dan Zhong, Xiaodong Sun. Development and application of chiral separation technology based on chiral metalorganic frameworks[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2024.101176
Citation:
Gege Zhu, Li Ge, Xinyu Li, Bing Niu, Qin Chen, Dan Zhong, Xiaodong Sun. Development and application of chiral separation technology based on chiral metalorganic frameworks[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2024.101176
Gege Zhu, Li Ge, Xinyu Li, Bing Niu, Qin Chen, Dan Zhong, Xiaodong Sun. Development and application of chiral separation technology based on chiral metalorganic frameworks[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2024.101176
Citation:
Gege Zhu, Li Ge, Xinyu Li, Bing Niu, Qin Chen, Dan Zhong, Xiaodong Sun. Development and application of chiral separation technology based on chiral metalorganic frameworks[J]. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2024.101176
1 Shanghai Engineering Research Center of Organ Repair, Joint International Research Laboratory of Biomaterials and Biotechnology in Organ Repair (Ministry of Education), School of Medicine, Shanghai University, Shanghai 200444, P. R. China;
2 Shanghai Key Laboratory of Bio-Energy Crops, School of Life Sciences, Shanghai University, Shanghai, 200444, P. R. China
Funds:
This study was fund by the National Natural Science Foundation of China (82473880 and 82003705) and the Shanghai Science and Technology Innovation Foundation (23010500200 and 23ZR1422700) and the Postdoctoral Fellowship Program of CPSF (GZC20231528).
Chirality is not only a natural phenomenon but also a bridge between chemistry and life sciences. An effective way to obtain a single enantiomer is through racemates resolution. Recent literature shows that chiral metal-organic frameworks (CMOFs) have many applications in various fields because of their diverse topologies and functionalities. This review outlines the design idea and summarizes the latest synthesis strategies and applications of CMOFs. It highlights key advances and issues in the separation domain. In conclusion, the review provides perspectives on the challenges and prospective advancements of CMOFs materials and CMOFs-based separation technologies.