Platycodin D inhibits angiogenic vascular mimicry in NSCLC by regulating the eIF4E-mediated RNA methylome

Shuyu Zheng; Yanlin Xin; Jiamin Lin; Zejuan Xie; Keyu Cheng; Shanshan Wang; Wenli Lu; Hao Yang; Tianming Lu; Jun Li; Ruogu Qi; Yuanyuan Guo

doi:10.1016/j.jpha.2023.10.003

Volume 14 Issue 1

Jan. 2024

Turn off MathJax

Article Contents

Article Navigation > Journal of Pharmaceutical Analysis > 2024 > 14(1): 152-155

Shuyu Zheng, Yanlin Xin, Jiamin Lin, Zejuan Xie, Keyu Cheng, Shanshan Wang, Wenli Lu, Hao Yang, Tianming Lu, Jun Li, Ruogu Qi, Yuanyuan Guo. Platycodin D inhibits angiogenic vascular mimicry in NSCLC by regulating the eIF4E-mediated RNA methylome[J]. Journal of Pharmaceutical Analysis, 2024, 14(1): 152-155. doi: 10.1016/j.jpha.2023.10.003

Citation:

Shuyu Zheng, Yanlin Xin, Jiamin Lin, Zejuan Xie, Keyu Cheng, Shanshan Wang, Wenli Lu, Hao Yang, Tianming Lu, Jun Li, Ruogu Qi, Yuanyuan Guo. Platycodin D inhibits angiogenic vascular mimicry in NSCLC by regulating the eIF4E-mediated RNA methylome[J]. Journal of Pharmaceutical Analysis, 2024, 14(1): 152-155. doi: 10.1016/j.jpha.2023.10.003

Citation:

Shuyu Zheng, Yanlin Xin, Jiamin Lin, Zejuan Xie, Keyu Cheng, Shanshan Wang, Wenli Lu, Hao Yang, Tianming Lu, Jun Li, Ruogu Qi, Yuanyuan Guo. Platycodin D inhibits angiogenic vascular mimicry in NSCLC by regulating the eIF4E-mediated RNA methylome[J]. Journal of Pharmaceutical Analysis, 2024, 14(1): 152-155. doi: 10.1016/j.jpha.2023.10.003

PDF( 2493 KB)

Platycodin D inhibits angiogenic vascular mimicry in NSCLC by regulating the eIF4E-mediated RNA methylome

doi: 10.1016/j.jpha.2023.10.003

a. Department of Biochemistry and Molecular Biology, School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China;
b. Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University, Hangzhou, 310009, China

Funds:

We thank Prof. Yang Zhao for his kind assistance in HUVEC cultivation and Dr. Xin for her kind assistance in data processing. This research was funded by the National Natural Science Foundation of China (Grant Nos.: 82004081 and 52073145) and the National Natural Science Foundation of Nanjing University of Chinese Medicine, China (Grant No.: NZY82004081).

Received Date: May 07, 2023
Accepted Date: Oct. 11, 2023
Rev Recd Date: Aug. 24, 2023
Publish Date: Oct. 14, 2023

Abstract

FullText(HTML)

References(4)

References

[1]	S.H. Choi, S.S. Yoo, S.Y. Lee, et al., Anti-angiogenesis revisited: reshaping the treatment landscape of advanced non-small cell lung cancer, Arch Pharm. Res. (Seoul) 45 (2022) 263-279.
[2]	M. Khan, A. Maryam, H. Zhang, et al., Killing cancer with platycodin D through multiple mechanisms, J. Cell Mol. Med. 20 (2016) 389-402.
[3]	S. Zheng, Z. Xie, Y. Xin, et al., Whole transcriptome analysis identifies platycodin D-mediated RNA regulatory network in non-small-cell lung cancer, Cells 11 (2022), 2360.
[4]	Y. Chen, H. Lin, L. Miao, et al., Role of N7-methylguanosine (m7G) in cancer, Trends Cell Biol. 32 (2022) 819-824.