Volume 15 Issue 4
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Yixuan Zhou, Yuelin Xu, Xiaoli Hou, Daozong Xia. Raman analysis of lipids in cells: Current applications and future prospects[J]. Journal of Pharmaceutical Analysis, 2025, 15(4): 101136. doi: 10.1016/j.jpha.2024.101136
Citation: Yixuan Zhou, Yuelin Xu, Xiaoli Hou, Daozong Xia. Raman analysis of lipids in cells: Current applications and future prospects[J]. Journal of Pharmaceutical Analysis, 2025, 15(4): 101136. doi: 10.1016/j.jpha.2024.101136
shu

Raman analysis of lipids in cells: Current applications and future prospects

doi: 10.1016/j.jpha.2024.101136

  • a. School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China;

  • b. Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou, 310053, China

Funds:

This work was supported by the National Natural Science Foundation of China (Grant NOs.: 82374169, and 82074085).

  • Received Date: Jun. 06, 2024
  • Accepted Date: Oct. 29, 2024
  • Rev Recd Date: Oct. 11, 2024
  • Publish Date: Nov. 01, 2024
    Abstract
  • Lipids play an important role in the regulation of cell life processes. Although there are various lipid detection methods, Raman spectroscopy, a non-invasive technique, provides the detailed chemical composition of lipid profiles without a complex sample preparation procedure and possesses greater potential in basic biology, clinical diagnosis and disease therapy. In this review, we summarized the characteristics and advantages of Raman-based techniques and their primary contribution to illustrating cellular lipid metabolism.
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